Clumber and Sussex Spaniels Only

Pyruvate dehydrogenase phosphatase deficiency (PDP1) is a rare condition in Clumber and Sussex Spaniels. It is a deficiency in the PDP1 enzyme, which regulates PDH. PDP1 deficiency is characterized by exercise intolerance and post exercise collapse. It is a simple autosomal recessive trait, and can be tested by means of a simple DNA test.

Tests are ordered online through the secure area of the OFA website. Payment is accepted by credit card (MasterCard and VISA). The OFA administers all order handling. Upon receipt of an order, the OFA will send out the test kit which will include a Foam-Tipped Applicator card for DNA sample collection, along with sample collection instructions. Using the FTA card technology, owners can safely collect DNA samples at home. The collection process is non-invasive, and no veterinary appointment is necessary.

Samples are then sent to the University of Missouri College of Veterinary Medicine where the samples will be processed by the Small Animal Molecular Genetics Lab. Results will be forwarded to the OFA, and the OFA will issue the resulting report to the owner.

The fee for each test includes the test kit, laboratory processing, and subsequent registration in the OFA databases.